Hi Valentin

How long and how hard do you brush your scalp?

Thanks

James

Sorry about typos, I’m on my Phone and autocorrect is in French

Massages work. I’v been able to regrow hair on areas bald since I’m 18 (I’m 33).
You don’t enough get recongnized as the absolue hero you are.

That said, there is still à thing I fins really perplexing about scalp tension theory:temple peaks.

Those small bits of hair framing thé face are affected by MPB, though thé skin underneath is regular, loose face skin (for me anyway, maybe I’m special, I Nevers poked other dudes head to verify).
I’m really curious if you had an explaination about that.

Also, I’m currently too broke to buy your method, so maybe you talk about it: brushing my scalp very hard with a plastic brush (and I added Lllt directly afterwards, but mainly the brushing) has been a réal game changer for me.

Maybe because of that, I’m on my way to be part of the luckies able to regrow litteraly 100% of my preteen hair

Hey Dante,

It’s great to hear from you. And thanks for sharing that study – very interesting stuff. For anyone interested: the investigation team stressed mice through one of three ways: short-term pain, restricted movement, and psychological stress. All three stressors led to faster depletion of melanocyte stem cells. The team then tested the mechanisms behind why this might be happening, specifically: a compromised immune system, the hormone corticosterone, and the hormone noradrenaline. Stressing mice with compromised immune systems and more corticosterone did not lead to faster graying rates; however, stressing mice injected with noradrenaline did – and demonstrated rapid depletion of melanocyte stem cells. So, it looks like we’re one step closer to understanding this process (and potentially how to tackle it).

Thanks a ton for sharing!

All my best,
Rob

https://www.nature.com/articles/s41586-020-1935-3

Title – ” Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells ”

Key Point – “Hair greying results from activation of the sympathetic nerves that innervate the melanocyte stem-cell niche. Under conditions of stress, the activation of these sympathetic nerves leads to burst release of the neurotransmitter noradrenaline (also known as norepinephrine). This causes quiescent melanocyte stem cells to proliferate rapidly, and is followed by their differentiation, migration and permanent depletion from the niche”