I want to ask about vitamin b3 (nicotinamide) WITH FLUSH does it increase NADPH, because i am taking it orally vitamin b3 to increase the blood circulation. So is vit b3 safe and does it increase NADPH as you mentioned in your article that 5-alpha reductase needs NADPH to convert free testosterone into DHT.

thank you
Allen

If i may i have a couple of short questions poised for you. I have been taking a Beta Blocker (Bisoprolol) for about 10 years, and until recently with all your research about inflammation and blood circulation of the scalp as well as online research side effects for this particular tablet can cause hair loss. I am now trying to set up some scans to cofirm the heart is fine with the aim of reducing and eventually comming off Bisoprolol altogether. the second point i would like to ask is about Rosemary Oil and a carrier such as Jojoba oil. Would this combination be worthwhile in helping blood circulation to the scalp combined with the massage techniques?. Many thanks

Try water cress instead.

I actually must apologize for this comment. I issued a question before fully readinng the article.

I realize I am being lazy now, but as a summer, is there an “noninvasive”, DHT-blocker you can recommend? I am about to try a laser therapy and want to combine it with a simple (yet good) DHT blocker, but there is no way I am going to go on finasteride.

Thanks for all your work,
Kacper

I understand that your concern is the goitrogenic effect, but if someone were to say consume broccoli sprouts (very high in Sulforaphane) and also eat a sufficient amount of iodine, would this actually be a problem? Wouldn’t it be beneficial?

Hi Chris , this sounds awful.

Robs links and paper will help you determine the cause.

I want to comment as recently I’ve been reading Hairloss forums to see how they reacted to new
information, posted before 2014-16.

One poster around 10 years ago nearly posted a similar concept as Rob and a few others regarding
blood flow and scalp tension/ and expansion.

The poster was ridiculed with abuse, and the main counter argument was that hair transplants work !

But you are definitely not alone. Many people who have undertaken this procedure have also lost their new transplanted hair , including celebs. For the same reason that the area of scalp is riddled with calcification , fibrosis and inflammation. Which eventually starves the healthy follicle over a period of time. This is why Fin is distributed by clinics after procedures.

This is why some people say that their transplants were a success five or seven years in, because they are on medication or the procedure was able to cause a certain amount of wound healing . I believe this is dependent on individual.

I hope you stay in touch and update us on your progress.

Regards.

Hey Chris,

Thanks for reaching out, and I’m sorry to hear about your experience with the failed hair transplants. If you’re interested, I wrote a bit about why / how this can happen in this paper…

http://www.medical-hypotheses.com/article/S0306-9877(17)31041-1/fulltext

…and this blog post:

https://perfecthairhealth.com/the-case-against-a-hair-transplant/

Are you currently taking finasteride or minoxidil? If so, for how long? And have you been taking them since your procedures?

Best,
Rob

Hey Alex,

It’s a great question! The short answer is that overall health and hair health aren’t perfectly correlated. After all, many professional athletes still lose their hair — so there has to be other factors involved.

And there are. When we look at the balding process, it’s extremely localized — i.e., only in areas above the galea aponeurotica (which is the dense fibrous membrane that stretches over the top parts of our scalps). There’s evidence that the balding process (which starts with inflammation) might in fact be mediated entirely by chronic tension — either in the galea aponeurotica or the skin. A response to tension is inflammation; a response to inflammation is DHT; and a response to chronic inflammation is eventually scarring.

This means you could eat the healthiest diet on the planet, exercise daily, but if you have a genetic predisposition to respond to chronic inflammation with DHT, and the scalp structure for chronic tension, you might still go bald.

Conversely, there are some overweight, out-of-shape people with absolutely no scalp tension at all.

I wrote a paper about this, which you can read here:

https://perfecthairhealth.com/update-2018-published-research-paper/

Best,
Rob